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Artropatías inflamatorias y artritis inducidas por microcristales


Líneas de investigación:

Artropatías microcristalinas – gota y artritis por pirofosfato.
Clasificación clínica de la gota dependiendo del manejo renal de urato.
Eficacia de los fármacos hipouricemiantes.
Determinación de los niveles adecuados para el control de la uricemia durante el tratamiento.
Establecimiento de distintas dianas terapéuticas de uricemia para tratamiento y prevención a largo plazo de la uricemia.
Factores de riesgo de mortalidad.
Desarrollo y validación de medidas de desenlace para el tratamiento hipouricemiante.
Medición de los tofos subcutáneos mediante calibradores y de los depósitos articulares mediante ecografía y resonancia nuclear magnética.



Integrantes del grupo

  Ana María Herrero Beites
 
 
  Javier Duruelo Echebarrieta
 
 
  Elena Garmendia Sánchez
 
 
  Joana Atxotegi Sáenz De Buruaga
 
 
  Javier Arostegui Lavilla
 
 
  María Del Consuelo Modesto Caballero
 
 
  Javier Arostegui Lavilla
 
 
  María Del Consuelo Modesto Caballero
 
 
  Javier Duruelo Echebarrieta
 
 

Publicaciones del grupo:

Gaztambide, Sonia, Ramirez, Joaquin, Gomez, Mercedes, Montalban, Coral, Ruiz, Rafael, Socias, Catalina, Boronat, Mauro, Aparicio, Cristina, Bilbao, Ismene, Conde, Santiago, Garcia-Cuartero, Beatriz, Jimenez, Belen, Rodriguez, Pilar, Perez, Elena, Hidalgo-Barquero, Emilia, Barrio, Raquel, Maria Gonzalez, Carmen, Rey Cordo, Carmen Lourdes, Cruz, Jaime, Hernandez, Jorge, Fernandez-Ramos, Concepcion, Marti, Juan, Clemente, Maria, Garcia, Leonor, Rica, Itxaso, Martinez, Rosa, Urrutia, Ines, Martinez de LaPiscina, Idoia, Santos, Fernando, Gil-Pena, Helena, Coto, Eliecer, Loredo, Vanessa, Ordonez, Flor Angel, Rodriguez, Julian, Braga Riera, Eva, Hernandez, Olaya, Fuente, Rocio, Claramunt, Debora, Garcia Nieto, Victor M., Claverie Martin, Felix, Gonzalez Acosta, Hilaria, Ramos Trujillo, Elena, Luis Yanes, Maria Isabel, Cordoba Lanus, Elizabeth, Castano, Luis, Madariaga, Leire, Perez de Nanclares, Gustavo, Garcia-Castano, Alejandro, Aguirre, Mireia, Herrero, Maria, Aguayo, Anibal, Ariceta, Gema, Meseguer, Anna, Spanish Endocrinology Grp, Renal Tube Grp. Novel mutations associated with inherited human calcium-sensing receptor disorders: A clinical genetic study. Eur. J. Endocrinol.. 2019; 180(1): 59 - 70. FI: 5,107(Q1). DOI: 10.1530/EJE-18-0129.

Dalbeth, Nicola, Jones, Graeme, Terkeltaub, Robert, Khanna, Dinesh, Fung, Maple, Baumgartner, Scott, Perez-Ruiz, Fernando. Efficacy and safety during extended treatment of lesinurad in combination with febuxostat in patients with tophaceous gout: CRYSTAL extension study. Arthritis Res Ther. 2019; 21(1): 8 - 8. FI: 4,148(Q2). DOI: 10.1186/s13075-018-1788-4.

Perez-Ruiz, Fernando, Dalbeth, Nicola. Combination urate-lowering therapy in the treatment of gout: What is the evidence?. Semin. Arthritis Rheum.. 2019; 48(4): 658 - 668. FI: 5,072(Q1). DOI: 10.1016/j.semarthrit.2018.06.004.

Bursill, David, Taylor, William J., Terkeltaub, Robert, Kuwabara, Masanari, Merriman, Tony R., Grainger, Rebecca, Pineda, Carlos, Louthrenoo, Worawit, Edwards, N. Lawrence, Andres, Mariano, Vargas-Santos, Ana Beatriz, Roddy, Edward, Pascart, Tristan, Lin, Ching-Tsai, Perez-Ruiz, Fernando, Tedeschi, Sara K., Kim, Seoyoung C., Harrold, Leslie R., McCarthy, Geraldine, Kumar, Nitin, Chapman, PeterT., Tausche, Anne-Kathrin, Vazquez-Mellado, Janitzia, Gutierrez, Marwin, Castelar-Pinheiro, Geraldo da Rocha, Richette, Pascal, Pascual, Eliseo, Fisher, Mark C., Burgos-Vargas, Ruben, Robinson, Philip C., Singh, Jasvinder A., Jansen, Tim L., Saag, Kenneth G., Slot, Ole, Uhlig, Tillmann, Solomon, Daniel H., Keenan, Robert T., Scire, Carlo Alberto, Biernat-Kaluza, Edyta, Dehlin, Mats, Nuki, George, Schlesinger, Naomi, Janssen, Matthijs, Stamp, Lisa K., Sivera, Francisca, Reginato, Anthony M., Jacobsson, Lennart, Liote, Frederic, Ea, Hang-Korng, Rosenthal, Ann, Bardin, Thomas, Choi, Hyon K., Hershfield, Michael S., Czegley, Christine, Choi, Sung Jae, Dalbeth, Nicola. Gout, Hyperuricemia, and Crystal-Associated Disease Network Consensus Statement Regarding Labels and Definitions for Disease Elements in Gout. Arthritis Care Res.. 2019; 71(3): 427 - 434. FI: 4,530(Q2). DOI: 10.1002/acr.23607.

Perez-Ruiz, Fernando, Jansen, Tim L., Tausche, Anne-Kathrin, Richette, Pascal, Liote, Frederic, So, Alexander K., Stack, Austin. Reassessing the Safety Profile of Lesinurad in Combination with Xanthine Oxidase Inhibitor Therapy. Rheumatol Ther. 2019; 6(1): 101 - 108. FI: (Q). DOI: 10.1007/s40744-019-0143-9.

Seoane-Mato, Daniel, Sanchez-Piedra, Carlos, Silva-Fernandez, Lucia, Sivera, Francisca, Blanco, Francisco J., Perez Ruiz, Fernando, Juan-Mas, Antonio, Pego-Reigosa, Jose M., Narvaez, Javier, Quilis Marti, Neus, Cortes Verdu, Raul, Anton-Pages, Fred, Quevedo Vila, Victor, Garrido Courel, Laura, del Val del Arno, Natividad, Paniagua Zudaire, Inmaculada, Anez Sturchio, Gustavo, Medina Varo, Fermin, del Mar Ruiz Tudela, Maria, Romero Perez, Antonio, Ballina, Javier, Brandy Garcia, Anahy, Fabregas Canales, Dolores, Font Gaya, Teresa, Bordoy Ferrer, Carolina, Gonzalez Alvarez, Beatriz, Casas Hernandez, Laura, Alvarez Reyes, Fatima, Delgado Sanchez, Monica, Martinez Dubois, Cristina, Angel Sanchez-Fernandez, Simon, Rojas Vargas, Luisa Marena, Garcia Morales, Paula Virginia, Olive, Alejandro, Rubio Munoz, Paula, Larrosa, Marta, Navarro Ricos, Noemi, Graell Martin, Eduard, Chamizo, Eugenio, Chaves Chaparro, Lara, Rojas Herrera, Sara, Pons Dolset, Jordi, Polo Ostariz, Miguel Angel, Ruiz-Alejos Garrido, Susana, Macia Villa, Cristina, Cruz Valenciano, Ana, Gonzalez Gomez, Maria Luisa, Morcillo Valle, Mercedes, Palma Sanchez, Deseada, Moreno Martinez, Maria Jose, Mayor Gonzalez, Marta, Saenz de Buruaga, Joana Atxotegi, Urionaguena Onaindia, Irati, Blanco Caceres, Boris Anthony, Diaz-Gonzalez, Federico, Bustabad, Sagrario. Prevalence of rheumatic diseases in adult population in Spain (EPISER 2016 study): Aims and methodology. Reumatol. Clin.. 2019; 15(2): 90 - 96. FI: (Q). DOI: 10.1016/j.reuma.2017.06.009.

Perez-Ruiz, Fernando. URICOSURIC DRUGS: OLD AND NEW. Rheumatology (Oxford). 2019; 58(3). FI: 5,149(Q1). DOI: .

Pablos, Jose L., Navarro, Federico, Blanco, Francisco J., Roman-Ivorra, Jose A., Alonso, Alberto, Martin Mola, Emilio, Cantalejo, Miguel, Ercole, Liliana, Rivero, Natividad. Efficacy of tocilizumab monotherapy after response to combined tocilizumab and methotrexate in patients with rheumatoid arthritis: the randomised JUST-ACT study. Clin. Exp. Rheumatol.. 2019; 37(3): 437 - 444. FI: 3,238(Q2). DOI: .

Pérez-Ruiz F, Jansen T, Tausche AK, Juárez-Campo M, Gurunath RK, Richette P. Efficacy and safety of lesinurad for the treatment of hyperuricemia in gout.. Drugs Context. 2019; 8: 212581 - 212581. FI: (Q). DOI: 10.7573/dic.212581.

Perez-Ruiz, Fernando, Richette, Pascal, Stack, Austin, Karra, Ravi, Garcia de Yebenes, Maria Jesus, Carmona, Loreto. FAILURE TO REACH SERUM URATE TARGET IS ASSOCIATED WITH ELEVATED MORTALITY IN GOUT. Ann. Rheum. Dis.. 2019; 78(2): 97 - 97. FI: 14,299(Q1). DOI: 10.1136/annrheumdis-2019-eular.5905.

Liote, Frederic, Karra, Ravi, Kandaswamy, Prashanth, Abhishek, Abhishek, Scire, Carlo Alberto, Perez-Ruiz, Fernando. AN ANALYSIS OF PRESCRIPTION RECORDS OF GOUT PATIENTS IN EUROPE: EVIDENCE OF SUBOPTIMAL MANAGEMENT AND CLINICAL INERTIA. Ann. Rheum. Dis.. 2019; 78(2): 1305 - 1306. FI: 14,299(Q1). DOI: 10.1136/annrheumdis-2019-eular.2868.

Irati, Urionaguena, Chinchilla Gallo, P. Sandra, Hernandez Gomez, Sandra, Garcia Llorente, Jose Francisco, Aizpurua Manso, Izaskun, Vegas Revenga, Nuria. DENSITOMETRY VALUES CHANGE WHEN STOPPING DENOSUMAB. Ann. Rheum. Dis.. 2019; 78(2): 1896 - 1896. FI: 14,299(Q1). DOI: 10.1136/annrheumdis-2019-eular.4338.

Presa, Maria, Perez-Ruiz, Fernando, Oyaguez, Itziar. 2ND LINE TREATMENT WITH LESINURAD AND ALLOPURINOL VERSUS FEBUXOSTAT FOR MANAGEMENT OF HYPERURICEMIA: A COST-EFFECTIVENESS ANALYSIS FOR SPANISH PATIENTS. Ann. Rheum. Dis.. 2019; 78(2): 291 - 291. FI: 14,299(Q1). DOI: 10.1136/annrheumdis-2019-eular.3231.

De Meulemeester, Marc, Jansen, Tim, Petersen, Gudula, Perez-Ruiz, Fernando. EUROPEAN PATIENT VOICE IN GOUT SURVEY - SUBJECTIVE SATISFACTION IN GOUT PATIENTS VERSUS OBJECTIVE SUBOPTIMAL GOUT CARE. Ann. Rheum. Dis.. 2019; 78(2): 153 - 154. FI: 14,299(Q1). DOI: 10.1136/annrheumdis-2019-eular.4873.

Richette, Pascal, Perez-Ruiz, Fernando, Karra, Ravi, Latourte, Augustin, Wild, Imane, Kandaswamy, Prashanth, Hagedorn, Heiko, Bardin, Thomas. FACTORS ASSOCIATED WITH EARLY FLARES WHEN INITIATING URATE LOWERING THERAPIES. POST HOC ANALYSIS OF CLEAR 1,2 AND CRYSTAL TRIALS. Ann. Rheum. Dis.. 2019; 78(2): 96 - 96. FI: 14,299(Q1). DOI: 10.1136/annrheumdis-2019-eular.4679.

Blanco Caceres, Boris Anthony, Perez-Ruiz, Fernando, Garcia Escudero, Paula, Gonzalez Fernandez, Marta. HOSPITAL ADMISSIONS IN PATIENTS WITH CHRONIC RHEUMATIC DISEASESRECEIVING ADALIMUMAB. DESCRIPTIVE STUDY OF A COHORT. Ann. Rheum. Dis.. 2019; 78(2): 2085 - 2086. FI: 14,299(Q1). DOI: 10.1136/annrheumdis-2019-eular.6405.

Garcia, Paula, Blanco Caceres, Boris Anthony, Perez-Ruiz, Fernando. IS THERE LIFE TO GOUT TREATMENT AFTER RHEUMATOLOGY IS OUT OF THE EQUATION?. Ann. Rheum. Dis.. 2019; 78(2): 1299 - 1299. FI: 14,299(Q1). DOI: 10.1136/annrheumdis-2019-eular.7091.

Garcia, Paula, Blanco Caceres, Boris Anthony, Perez-Ruiz, Fernando. LONG-TERM URATE-LOWERING THERAPY: IS IT `ALL LIFELONG' NECESSARY?. Ann. Rheum. Dis.. 2019; 78(2): 1299 - 1300. FI: 14,299(Q1). DOI: 10.1136/annrheumdis-2019-eular.7618.

Quilis Marti, Neus, Vela-Casasempere, Paloma, Blanco Caceres, Boris Anthony, Diaz Torne, Cesar, Calvo-Aranda, Enrique, Sivera, Francisca, Prada-Ojeda, Alejandro, Perez-Ruiz, Fernando, Pascual, Eliseo, Andres, Mariano. SKIN ADVERSE EVENTS WITH FEBUXOSTAT IN GOUT PATIENTSWITH PREVIOUS SKIN REACTIONS TO ALLOPURINOL. A MULTICENTRE DESCRIPTIVE STUDY. Ann. Rheum. Dis.. 2019; 78(2): 1309 - 1310. FI: 14,299(Q1). DOI: 10.1136/annrheumdis-2019-eular.4394.

Blanco Caceres, Boris Anthony, Garcia Escudero, Paula, Arostegui Lavilla, Javier, Rivas Zavaleta, Mayra Nathali, Gonzalez Fernandez, Marta. VITAMIN D (25OHD) IN PATIENTS WITH CHRONIC RHEUMATIC DISEASESRECEIVING TREATMENT WITH ADALIMUMAB. DESCRIPTIVE STUDY OF A COHORT. Ann. Rheum. Dis.. 2019; 78(2): 1882 - 1882. FI: 14,299(Q1). DOI: 10.1136/annrheumdis-2019-eular.7012.

Perez Ruiz, Fernando, Richette, Pascal, Stack, Austin G., Gurunath, Ravichandra Karra, Garcia de Yebenes, Ma Jesus, Carmona, Loreto. Failure to reach uric acid target of < 0.36 mmol/L in hyperuricaemia of gout is associated with elevated total and cardiovascular mortality. RMD Open. 2019; 5(2): UNSP e001015. FI: (Q). DOI: 10.1136/rmdopen-2019-001015.

Blanco Caceres, B. A., Garcia Escudero, P., Gonzalez Fernandez, M.. VITAMIN D (25OHD) IN PATIENTS WITH CHRONIC RHEUMATIC DISEASES RECEIVING TREATMENT WITH ADALIMUMAB: DESCRIPTIVE STUDY OF A COHORT. Osteoporosis Int.. 2019; 30(2): 755 - 756. FI: 3,819(Q2). DOI: .

Dalbeth, Nicola, Choi, Hyon K., Joosten, Leo A. B., Khanna, Puja P., Matsuo, Hirotaka, Perez-Ruiz, Fernando, Stamp, Lisa K.. Gout. Nat. Rev. Dis. Primers. 2019; 5(1): 69 - 69. FI: 32,274(Q1). DOI: 10.1038/s41572-019-0115-y.

Sumpter, Nicholas, Merriman, Tony, Reynolds, Richard, Abhishek, Abhishek, Andres, Mariano, Dalbeth, Nicola, Doherty, Michael, Jacobsson, Lennart, Janssen, Matthijs, Jansen, Tim, Joosten, Leo, Kapetanovic, Meliha, Liote, Frederic, Matsuo, Hirotaka, McCarthy, Geraldine, Perez-Ruiz, Fernando, Riches, Philip, Richette, Pascal, Roddy, Edward, Stiburkova, Blanka, So, Alex, Stamp, Lisa, Tausche, Anne-Kathrin, Torres-Jimenez, Rosa, Uhlig, Till. Association of a Gout Polygenic Risk Score with Disease Severity Phenotypes Amongst Caucasian Gout Patients in Three Independent Cohorts. Arthritis Rheumatol.. 2019; 71(10). FI: 9,002(Q1). DOI: .

Bursill, David, Taylor, William J., Terkeltaub, Robert, Abhishek, Abhishek, So, Alexander K., Vargas-Santos, Ana Beatriz, Gaffo, Angelo Lino, Rosenthal, Ann, Tausche, Anne-Kathrin, Reginato, Anthony, Manger, Bernhard, Scire, Carlo, Pineda, Carlos, van Durme, Caroline, Lin, Ching-Tsai, Yin, Congcong, Albert, Daniel Arthur, Biernat-Kaluza, Edyta, Roddy, Edward, Pascual, Eliseo, Becce, Fabio, Perez-Ruiz, Fernando, Sivera, Francisca, Liote, Frederic, Schett, Georg, Nuki, George, Filippou, Georgios, McCarthy, Geraldine, Castelar Pinheiro, Geraldo da Rocha, Ea, Hang-Korng, Tupinamba, Helena De Almeida, Yamanaka, Hisashi, Choi, Hyon K., Mackay, James, ODell, James R., Vazquez Mellado, Janitzia, Singh, Jasvinder A., Fitzgerald, John D., Jacobsson, Lennart T. H., Joosten, Leo, Harrold, Leslie R., Stamp, Lisa, Andres, Mariano, Gutierrez, Marwin, Kuwabara, Masanari, Dehlin, Mats, Janssen, Matthijs, Doherty, Michael, Hershfield, Michael S., Pillinger, Michael, Edwards, N. Lawrence, Schlesinger, Naomi, Kumar, Nitin, Slot, Ole, Ottaviani, Sebastien, Richette, Pascal, MacMullan, Paul A., Chapman, Peter T., Lipsky, Peter E., Robinson, Philip, Khanna, Puja P., Gancheva, Rada N., Grainger, Rebecca, Johnson, Richard J., Te Kampe, Ritch, Keenan, Robert T., Tedeschi, Sara K., Kim, Seoyoung, Choi, Sung Jae, Fields, Theodore R., Bardin, Thomas, Uhlig, Till, Jansen, Tim, Merriman, Tony, Pascart, Tristan, Neogi, Tuhina, Kluck, Viola, Louthrenoo, Worawit, Dalbeth, Nicola. Gout, Hyperuricaemia and Crystal-Associated Disease Network (G-CAN) consensus statement regarding labels and definitions of disease states of gout. Ann. Rheum. Dis.. 2019; 78(11): 1592 - 1600. FI: 14,299(Q1). DOI: 10.1136/annrheumdis-2019-215933.

Perez-Ruiz, Fernando, Dalbeth, Nicola. Gout. Rheum. Dis. Clin. North Am.. 2019; 45(4): 583 - 583. FI: 3,527(Q2). DOI: 10.1016/j.rdc.2019.08.001.

Presa, Maria, Perez-Ruiz, Fernando, Oyaguez, Itziar. Second-line treatment with lesinurad and allopurinol versus febuxostat for management of hyperuricemia: a cost-effectiveness analysis for Spanish patients. Clin. Rheumatol.. 2019; 38(12): 3521 - 3528. FI: 2,293(Q3). DOI: 10.1007/s10067-019-04739-3.

Perez-Ruiz F, Kandaswamy P, Gurunath RK, Burton H, Jansen T. A summary of clinical evidence for commonly used uricosurics for gout in europe. Ann. Rheum. Dis. 2018; 77(2): 1045 - 1045 MEETING ABSTRACT.

Perez-Ruiz I, Meijide S, Hernandez ML, Navarro R, Ferrando M, Larreategui Z, et al. Antioxidant status of human follicular fluid: natural versus controlled ovarian hyper-stimulated cycles. Free Radic. Biol. Med. 2018; 120(1): 62 - 62. MEETING ABSTRACT.

Perez-Ruiz F, Chinchilla SP, Atxotegi J. Association between hfe genotypes and clinical severity characteristics of calcium pyrophosphate crystal arthritis. Ann. Rheum. Dis. 2018; 77(2): 140 - 141. MEETING ABSTRACT.

Perez-Ruiz F, Atxotegi J. Association of HFE Genotypes with Clinical Severity in Patients with Definite Calcium Pyrophosphate Arthritis. Arthritis Rheumatol.. 2018; 70(9). MEETING ABSTRACT.

Perez-Ruiz F, Richette P, Karra RG, Wild I, Hagedorn H, Kandaswamy P, et al. Effect of serum uric acid (sua) on gout flares (gf) and tophi resolution in gout patients. Pooled post hoc analysis of clear 1 & clear 2 trials. Ann. Rheum. Dis. 2018; 77(2): 658 - 659. MEETING ABSTRACT.

Sanmarti R, Tornero-Molina J, Narvaez FJ, Munoz A, Garmendia E, Ortiz-Garcia AM, et al. Efficacy and Safety of Corticosteroids in Rheumatoid Arthritis: Systematic Literature Review and Practical Recommendations. Arthritis Rheumatol.. 2018; 70(9). MEETING ABSTRACT.

Kiltz U, Perez-Ruiz F, Uhlig T, Jansen TL, Karra R, Schmedt N, et al. Epidemiology, treatment, and health resource use of gout patients in germany: results from analysis of a claims database. Value Health. 2018; 21: 7 - 7. MEETING ABSTRACT.

Shaukat A, Gosling A, Bixley M, Phipps-Green A, Major TJ, Cadzow M, et al. Evaluating a Causal Role of Mitochondrial Variation in the Development of Gout. Arthritis Rheumatol. 2018; 70(9). MEETING ABSTRACT.

Perez-Ruiz F, Richette P, Stack A, Gurunath RK, Yprous MJGD, Carmona L. Failure to Reach Serum Urate Target Is Associated with Elevated Mortality in Gout. Arthritis Rheumatol. 2018; 70(9). MEETING ABSTRACT.

Perez-Ruiz I, Martinez G, Hernandez ML, Navarro R, Ferrando M, Larreategui Z, et al. Human granulosa cells express proteins of the paraoxonase family. Free Radic. Biol. Med. 2018; 120(1): 138 - 138. MEETING ABSTRACT.

Perez-Ruiz F, Sanchez-Piedra CA, Sanchez-Costa JT, Andrés M, Diaz-Torne C, Jimenez-Palop M, et al. Improvement in Diagnosis and Treat-to-Target Management of Hyperuricemia in Gout: Results from the GEMA-2 Transversal Study on Practice. Rheumatol. Ther.. 2018; 5(1): 243 - 253. FI: (Q). DOI: 10.1007/s40744-017-0091-1.

Perez-Ruiz F, Desideri G. Improving adherence to gout therapy: an expert review. Therap. Clin. Risk Manag.. 2018; 14: 793 - 802. FI: 1,995(Q3). DOI: 10.2147/TCRM.S162956. REVIEW.

Chinchilla SP, Atxotegi J, Onaindia IU, Perez-Ruiz F. Rheumatology talks to the community: results of an educational intervention. Ann. Rheum. Dis. 2018; 77(2): 868 - 868. MEETING ABSTRACT.

Cohen SB, Alonso-Ruiz A, Klimiuk PA, Lee EC, Peter N, Sonderegger I, et al. Similar efficacy, safety and immunogenicity of adalimumab biosimilar BI 695501 and Humira reference product in patients with moderately to severely active rheumatoid arthritis: results from the phase III randomised VOLTAIRE-RA equivalence study. Ann. Rheum. Dis. 2018; 77(6): 914 - 921. FI: 12,350(Q1). DOI: 10.1136/annrheumdis-2017-212245.

Zaidi F, Phipps-Green A, Tausche AK, So A, Riches P, Andres M, et al. Systematic Genetic Analysis of Early-Onset Gout: ABCG2 141K Is the Strongest Predictor. Arthritis Rheumatol. 2018; 70(9). MEETING ABSTRACT.

Kumar AUA, Browne LD, Li X, Adeeb F, Perez-Ruiz F, Fraser AD, et al. Temporal trends in hyperuricaemia in the Irish health system from 2006-2014: A cohort study. PLoS One. 2018; 13(5): e0198197. FI: 2,766(Q1). DOI: 10.1371/journal.pone.0198197.

Kiltz U, Perez-Ruiz F, Uhlig T, Jansen TL, Gurunath RK, Schmedt N, et al. The Prevalence and Incidence of Gout, Its Associated Comorbidities and Treatment Pattern: An Epidemiological Study from Germany. Arthritis Rheumatol.. 2018; 70(9). MEETING ABSTRACT.

Uson J, Garmendia E, Moragues C, de Agustin JJ, Mayordomo L, de Miguel E, et al. To what extent is interobserver reliability for detecting ultrasound urate crystal deposits dependent on the experience of the ultrasonographer?. Ann. Rheum. Dis. 2018; 77(2): 809 - 809. MEETING ABSTRACT.

Perez-Ruiz F, Moreno-Lledo A, Urionaguena I, Dickson AJ. Treat to target in gout. RHEUMATOLOGY. 2018; 57(1): 20 - 26. FI: 5,245(Q1). DOI: 10.1093/rheumatology/kex442. REVIEW.

Latourte A, Soumare A, Bardin T, Perez-Ruiz F, Debette S, Richette P. Uric acid and incident dementia over 12 years of follow-up: a population-based cohort study. Ann. Rheum. Dis. 2018; 77(3): 328 - 335. FI: 12,350(Q1). DOI: 10.1136/annrheumdis-2016-210767.

Gaffo AL, Dalbeth N, Saag KG, Singh JA, Rahn EJ, Mudano AS, et al. Validation of a Definition of Flare in Patients With Established Gout. Arthritis Rheumatol. 2018; 70(3): 462 - 467. FI: 7,871(Q1). DOI: 10.1002/art.40381.

Alvaro-Gracia JM, Jover JA, Garcia-Vicuna R, Carreno L, Alonso A, Marsal S, et al. Intravenous administration of expanded allogeneic adipose-derived; mesenchymal stem cells in refractory rheumatoid arthritis (Cx611):; results of a multicentre, dose escalation, randomised, single-blind,; placebo-controlled phase Ib/Ila clinical trial. Ann Rheum Dis. 2017;76:196-202. FI:12,811(Q1). DOI:10.1136/annrheumdis-2015-208918.

Barber RM, Fullman N, Sorensen RJD, Bollyky T, McKee M, Nolte E, et al. Healthcare Access and Quality Index based on mortality from causes amenable to personal health care in 195 countries and territories 1990-2015:a novel analysis from the Global Burden of Disease Study 2015. Lancet. 2017;390:231-66. FI:47,831(Q1). DOI:10.1016/S0140-6736(17)30818-8.

Chinchilla S, Urionaguena I and Perez-Ruiz F. Are We Ready? Changes in the Profile of Gout Patients over the Last 25; Years. Arthritis Rheumatol. 2017; . FI: 6,918(Q1). DOI: .

Chinchilla SP, Urionaguena I and Perez-Ruiz F. Ready or not? Changes in the clinical profile of gout patients over the last 25 years. Ann. Rheum. Dis. 2017; 76: 381-0. FI: 12,811(Q1). DOI: 10.1136/annrheumdis-2017-eular.5459.

Cohen S, Alonso-Ruiz A, Klimiuk PA, Lee E, Peter N, Sonderegger I, et al. Similar efficacy and safety of biosimilar candidate bi 695501 and adalimumab originator reference product in patients with moderate to severe active rheumatoid arthritis: 24 week results from a phase iii clinical study (Voltaire (R)-RA). Ann Rheum Dis. 2017;76:553. FI:12,811(Q1). DOI:10.1136/annrheumdis-2017-eular.3405. ABSTRACT

Cohen S, Genovese MC, Choy E, Perez-Ruiz F, Matsumoto A, Pavelka K, et al. Efficacy and safety of the biosimilar ABP 501 compared with adalimumab in patients with moderate to severe rheumatoid arthritis:a randomized double-blind phase III equivalence study. Ann Rheum Dis. 2017;76:1679-87. FI:12,811(Q1). DOI:10.1136/annrheumdis-2016-210459.

Cohen SB, Alonso-Ruiz A, Klimiuk PA, Lee E, Peter N, Czeloth N, et al. Biosimilar Candidate BI 695501 and Adalimumab Reference Product Have Similar Efficacy and Safety in Patients with Moderately-to-Severely Active Rheumatoid Arthritis (RA): 1-Year Results from a Phase III Study. Arthritis Rheumatol. 2017;69:2442 . FI:6,918(Q1). ABSTRACT.

Cutolo M, Cimmino MA, Perez-Ruiz F. Potency on lowering serum uric acid in gout patients a pooled analysis of registrative studies comparing febuxostat vs allopurinol. Eur Rev Med Pharmacol Sci. 2017;21:4186-95. FI:1,778(Q3).

Dalbeth N, Jones G, Terkeltaub R, Khanna D, Kopicko J, Bhakta N, et al. Lesinurad, a Selective Uric Acid Reabsorption Inhibitor in Combination With Febuxostat in Patients With Tophaceous Gout Findings of a Phase III Clinical Trial. Arthritis Rheumatol. 2017;69:1903-13. FI:6,918(Q1). DOI:10.1002/art.40159.

Gaffo AL, Dalbeth N, Saag K, Singh JA, Rahn EJ, Mudano AS, et al. Validation of a definition for flare in patients with established gout. Arthritis Rheumatol. 2017;69:2950. FI:6,918(Q1). ABSTRACT

Kiltz U, Smolen J, Bardin T, Cohen Solal A, Dalbeth N, Doherty M, et al. Treat-to-target (T2T) recommendations for gout. Ann Rheum Dis. 2017;76:632-8. FI:12,811(Q1). DOI:10.1136/annrheumdis-2016-209467.

Liu S, Perez-Ruiz F, Miner JN. Patients with gout differ from healthy subjects in renal response to changes in serum uric acid. Joint Bone Spine. 2017;84:183-8. FI:3,329(Q2). DOI:10.1016/j.jbspin.2016.04.007.

Merriman TR, Cadzow M, Merriman ME, Phipps-Green A, Topless R, Abhishek A, et al. A genome-wide association study of gout in people of European ancestry. Arthritis Rheumatol. 2017;69:1104. FI:6,918(Q1). ABSTRACT

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